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Online peer support for people with long-term conditions

Deadline
Who

•  150 adults with long-term physical health conditions, including Parkinson’s

•  Unfortunately, people who have been diagnosed with dementia or a severe mental illness (bipolar disorder, schizophrenia, post-traumatic stress disorder, and/or psychosis) are unable to take part
 

Where
From home

You will be asked to fill out questionnaires about your experiences using the new website or NHS mental health resources. This research is led by the King's College London. 

  • I can do at home
  • Questionnaires
Distance: From home

Assessing mood and behaviour using a smartphone application

Deadline
Who

People living in the UK aged between 18-80 who have access to an iPhone/iPad or Android smartphone/tablet, and belong to any one of the following groups: 

•  300 people with Parkinson’s

•  300 people unaffected by any psychiatric or neurological condition

•  300 people with a history of anxiety or mood disorder but no diagnosis of a neurological condition

Where
From home

You will be asked to download an app to your smartphone or tablet and asked to play a short decision-making game and complete surveys that take 3-5 minutes each. The time spent on the app will be no more than 10 minutes per day for the duration of the 3-week study. 

This research is led by University College London. 

  • Studying symptoms
Distance: From home

Developing talking therapy for people with Parkinson’s who experience anxiety

Deadline
Who

•  15 people with Parkinson’s who experience anxiety 
•  15 health professionals working with people affected by Parkinson’s
 

Where
From home

You will be asked to take part in a 1-hour interview about what may help or hinder people with Parkinson’s ability to take part in talking therapy. You can take part in this research over the telephone or online via a video call. 

The research is led by University College London. It is part of the AND-PD study, looking at anxiety and Parkinson’s and a wider project around Acceptance and Commitment Therapy for people with Parkinson’s. 

  • I can do at home
  • Treatments or therapies
Distance: From home

Understanding the experience of hearing loss in people with Parkinson’s dementia

Deadline
Who

• 10 people with Parkinson’s dementia who are experiencing hearing loss

• 10 people with Dementia with Lewy Bodies who are experiencing hearing loss

• 10 unpaid carers for people with Parkinson’s dementia or Dementia with Lewy Bodies who are experiencing hearing loss

Everyone taking part must have access to a device that connects to the internet at home such as a computer, smartphone or tablet.

Where
From home

You will be asked to take part in an online hearing test and interview. This research is led by Liverpool University.

  • I can do at home
  • Studying symptoms
Distance: From home

Get it on time: Parkinson's medication management while in hospital

Deadline
Who

350 people with Parkinson’s 

• who are taking Parkinson’s medication

• have recently attended a hospital visit or have a visit planned in the near future

Where
From home

You will be asked to complete one survey per month for 6 months following a hospital visit. The surveys can be completed online or by post. 

This research is led by Manchester Metropolitan University. 

  • Care and services
  • Questionnaires
Distance: From home
A woman holding a tablet is talking to a doctor via a video call.

Exploring how people in Ireland view Parkinson’s

Deadline
Who

• 6 people with Parkinson’s to take part in an interview 

• 8 healthcare professionals who specialise in Parkinson’s to take part in a focus group 

• Everyone who takes part must live in Ireland 

Where
From home

You can take part in this research over the telephone, face-to-face, or online. 

This research is led by Queen’s University Belfast. 

  • Care and services
Distance: From home

Tracking Parkinson’s symptoms, medications, and menstruation

Deadline
Who

200 women with Parkinson’s
•   The researcher’s are interested in recruitment of all women at different hormonal stages of their life, i.e. menstruating, post-menopausal and pregnant

•   You can take part if you are based in the UK, Europe or the USA

Where
From home

You'll be asked to use a digital menstruation and Parkinson's symptoms tracking app for 4 months and feedback on your experience. This research is led by University College Cork.

  • Studying symptoms
Distance: From home

Parkinson’s and Movement Disorders Families Project

Deadline
Who

• 2400 people with Parkinson’s, or another movement disorder, who have either:

•  developed the condition before the age of 45,

• or have a family history of other family members with the condition, 

• or who carry a known gene change associated with the condition 

Where
Central London (Hampsted), Central London (Queen Square), South London, North London, East London, West London, Cornwall, Isle of Wight, Basingstoke, Poole, Worthing, Harrogate, Sheffield, Salisbury, Romford, Leeds, Uxbridge, Leicester, Keighley, Exeter, Plymouth, Taunton, Yeovil, Llandudno, Shrewsbury, Middlesbrough, Scarborough, Solent, Wolverhampton, Sunderland, Luton, Cumbria, Basildon, Coventry, Birmingham, Pennines, Norwich, Christchurch, Cambridge, Northumbria

Taking part involves 1 research site visit, giving a blood sample, and completing surveys and assessments of your movement. This research is led by University College London. 

  • Biological samples
Distance: 0.7 miles

Can a wearable device improve walking for people with Parkinson's?

Deadline
Who

60 people with Parkinson’s who experience freezing while walking (feeling like your feet are ‘glued’ to the ground).

30 people without Parkinson’s or any other condition that affects walking or balance. 

All participants must be able to walk without the aid of another person for at least 3 minutes and have normal or corrected-to-normal vision.

Unfortunately, people using a deep brain stimulator (DBS), a pacemaker or those with an injury that affects balance and walking are unable to take part. 

Where
Exeter

Taking part involves attending 1 or 2 visits to a research centre at the University of Exeter to trial a new cueing device. 

  • Treatments or therapies
Distance: 37.3 miles

Understanding the role of gut hormones in dementia

Deadline
Who

All participants must be over the age of 60, with a Body Mass Index (BMI) of less than 30, and be from the following groups: 
• 10 people with Parkinson’s
• 10 people with Parkinson’s dementia
• 10 people with Alzheimer’s Disease
• 10 people with Dementia with Lewy Bodies
• 10 people without any of the above 4 conditions

All participants must be living in South and Southwest Wales and be happy to travel to the research site in Swansea.

Where
Swansea

You will be invited to attend 2 visits to the research centre. The first visit will involve completing surveys to understand mental processes and movement. During the second visit, blood samples will be collected from you on arrival and at regular intervals following a breakfast provided by the research team. 

This research is led by Dr Jeff Davies at Swansea University. 

  • Biological samples
  • Studying symptoms
Distance: 84.5 miles

CAN-PDP: Cannabidiol (CBD) for people with Parkinson's who experience hallucinations or delusions

Deadline
Who

120 people with Parkinson’s who:

• are over 40 years old

• have experienced any symptoms of psychosis for at least one month. This could include seeing, hearing, or feeling things that aren’t there and mistaking objects for other things (hallucinations). For example, a pile of clothes might look like a dog. Symptoms could also include unusual thoughts, beliefs, or worries that aren't based on reality (delusions)

• have been taking any Parkinson’s medications for at least one month

• are not taking clozapine

• and have someone who can attend study visits with them

Where
King’s College Hospital, South London and Maudsley, South West London, Bath, Sheffield , Chertsey , Derby , Newport, Llanelli , Wrexham, Bodmin, Dundee , Pembrokeshire, South Tyneside & Sunderland

Taking part involves taking the study treatment (CBD) or a placebo treatment (such as a sugar pill) for 12 weeks, and attending up to 6 assessment visits. Some of these can take place over the telephone or online, and others will need to take place at your local research centre or at your home.

  • Treatments or therapies
Distance: 95.6 miles

The Parkinson’s Progression Markers Initiative: How does Parkinson’s start and change?

Deadline
Who

You may be eligible to participate if you fit the criteria of one of the following groups: 

• Aged 60+ and are first-degree family members (parent, child, sibling) of a person with Parkinson’s,
• Aged 60+ who act out their dreams while asleep or who have a genetic mutation linked to PD or who experience sustained smell loss,
• Aged 56+ who haven’t been diagnosed with Parkinson’s and no known risk

Where
Newcastle upon Tyne, Oxford, West London, East London

Taking part involves 4 study visits in one year and 2 visits in the second year. At each visit, you will complete physical and neurological exams, memory tests, and brain scans. 

  • Brain scans
  • Studying symptoms
Distance: 157.2 miles

What might cause problems in managing impulse control for people with Parkinson’s?

Deadline
Who

• 20 people with Parkinson’s who are not taking Parkinson’s medication 

• 20 people with Parkinson’s who are taking ropinirole (also known as Requip, Repinex, Aimpart, Ippinia, Ralnea, Raponer, Ropilynz, Ropiqual, or Spiroco) as part of their medications

Where
Birmingham

You will be asked to attend 2 research visits, which involve completing tasks while your brain activity is recorded. 

This research is led by the University of Birmingham. 

  • Studying symptoms
Distance: 170.4 miles

COBALT: Trial of a combination of 2 drugs as a Parkinson’s dementia treatment

Deadline
Who

300 people with Parkinson’s dementia or dementia with Lewy Bodies 
• who are aged over 55
• have been taking an acetylcholinesterase inhibitor (AChEI) medication (for example, Donepezil also called Aricept) for at least 12 weeks

All participants will be asked to take part with a trial partner such as a loved one or carer. 

Where
West London , Cambridge, Bodmin, Cornwall, Cupar, Fife, Hamilton, South Lanarkshire, Glasgow, Bristol, Nottingham, Darlington, Beckenham, Southampton, Maidstone, Exeter, Norwich, Sheffield, Romford, Gloucester, Newcastle upon Tyne, Worthing, Oxford, North West London , Edinburgh, Chertsey, South West London, Bradford

You will be asked to take either the study drugs or a placebo drug for 52 weeks and attend 3 in-person visits at your local research hospital or at home. 

  • Treatments or therapies
Distance: 183.7 miles

AND-PD: Anxiety (with and without features of depression) in people with Parkinson's.

Deadline
Who

20 people without Parkinson's, 

 • aged between 65 and 75 years old,

 • who experience feelings of anxiety such as worry or restlessness

The research team is particularly looking for people from ethnic minorities to take part. 

Where
North London, South London

Over a 1 year period, you will attend 4 research visits at the research site or online from home.  At each visit, you will complete a series of questionnaires and take part in assessments. This research is led by Professor Annette Schrag at University College London, and King's College London.

  • I can do at home
  • Studying symptoms
Distance: 189.6 miles

Could looking at the breakdown of caffeine in the body help us to identify Parkinson’s?

Deadline
Who

100 people with Parkinson’s 
•  50 people who are taking medication for their condition
•  50 people who are not taking medication for their condition 


100 people without Parkinson’s 
•  who don’t have any pre-existing neurological conditions 

Where
Denbighshire, Wrexham

You will be asked to attend 5 visits to your local research hospital over an 18-month period. 

This research is led by Betsi Cadwaladr University. 

  • Studying symptoms
Distance: 189.7 miles

Study of variations of AQP4 gene in people with Parkinson’s

Deadline
Who

400 people diagnosed with Parkinson’s who are,

• aged between 18 and 85 years

• and comfortable using the internet and technology

Where
London

You will need to attend the research facility at King’s College Hospital for an initial 50-minute appointment where a blood sample will be taken and be shown how to use an Actigraph, a wrist-worn device.

  • Biological samples
  • Studying symptoms
Distance: 190.1 miles

How the brain works in people with Parkinson’s

Deadline
Who

20 people with Parkinson’s and 20 people without Parkinson’s,

• who are 40 years old or older

• don’t experience hallucinations or delusions (psychosis)

• are not participating in any clinical trial involving taking a study medication

Where
London

You will be asked to attend 1 study visit, which will last 2-4 hours. The visit will involve an MRI scan and surveys. 

This research is led by Sara Pisani at Kings College London. 

  • Brain scans
Distance: 190.3 miles

Weight-shift training to overcome freezing when walking

Deadline
Who

50 people with Parkinson’s who are:

•  aged 55 or above

•  experience freezing at home when walking (feeling like your feet are 'glued' to the ground)

•  able to walk from one room to another without support while ‘off’ medication

Unfortunately, this research is not suitable for those who have undergone DBS surgery or use a Levodopa pump, or experience significant memory or balance problems

Where
Take part from your home in London, Take part from your home in Exeter

You will be asked to take part in walking tests and a training program using videos from your home. 

  • Treatments or therapies
Distance: 190.3 miles
Valsala Benn and her husband David, fill in forms and take medication.

Clinical trial of obeticholic acid to improve thinking and memory problems

Deadline
Who

25 people with Parkinson’s 
•  who are aged between 18 and 79 
•  and experience mild cognitive impairment, such as issues with remembering things, feelings of distraction or disorganisation, and finding it difficult to plan and accomplish tasks

Where
Newcastle

You will be asked to take the trial medication, obeticholic acid, or a placebo for 6 months.

This research is funded by a company called Intercept Pharmaceuticals, who make the Obeticholic Acid drug. Intercept Pharmaceuticals are based outside of the UK in the United States.

  • Treatments or therapies
Distance: 333.4 miles

Tracking eye movements to identify people with Parkinson’s

Deadline
Who

•  40 people with Parkinson’s, and
•  40 people without Parkinson’s 
•  with no significant eye conditions 

Unfortunately people with other neurological conditions such as dementia are unable to take part.

Where
Newcastle

You will be asked to take part in a 1 hour assessment of balance, problem solving and eye movements at Northumbria University. People with Parkinson's can also take part in an optional extra assessment from home.

  • Studying symptoms
Distance: 336.2 miles

Changes in gut bacteria of newly diagnosed people with Parkinson’s

Deadline
Who

•  40 people with Parkinson’s diagnosed within the last six months, or longer if they have not started medication yet


•  40 people without Parkinson’s from the same household 

Where
Aberdeen

You will be asked to attend 2 research centre visits which will involve questionnaires and physical examinations.

This research is led by the University of Aberdeen. 

  • Biological samples
  • Studying symptoms
Distance: 474.5 miles