Research teams across the UK aim to investigate whether CBD is an effective treatment for hallucinations and delusions.
120 people with Parkinson’s who:
• are over 40 years old
• have experienced any symptoms of psychosis for at least one month. This could include seeing, hearing, or feeling things that aren’t there and mistaking objects for other things (hallucinations). For example, a pile of clothes might look like a dog. Symptoms could also include unusual thoughts, beliefs, or worries that aren't based on reality (delusions)
• have been taking any Parkinson’s medications for at least one month
• are not taking clozapine
• and have someone who can attend study visits with them
If you are eligible to take part, you will either receive the study treatment (CBD) or a placebo treatment (such as a sugar pill) for 12 weeks.
You will be asked to attend up to 6 visits. Some of these can take place over the telephone or online, and others will need to take place at your local research centre or at your home. Each visit will last between 1 and 3 hours. During the visits, you may be asked to give blood samples, complete surveys, or physical examinations.
You can also optionally take part in 2 MRI scans.
Find more information in the following participant information sheets:
Interested in taking part?
Scroll down to find your nearest study site location, click on the arrow and contact the relevant research team.
The deadline for taking part in this research is 1 March 2025.
If you have any questions, please contact the Research Team by email at [email protected].
This is a phase 2 research study. Previous studies suggest that CBD may be useful in treating symptoms of psychosis, they also suggest that it is safe to use in older adults. Find out more about the different phases of medical research.
Email: [email protected]
There is also a research site at South London and Maudsley NHS Foundation Trust, Michael Rutter Centre, London SE5 8AZ. Please contact Sara Pisani using the above contact details if you'd like to take part at the Michael Rutter Centre.