CAN-PDP: Cannabidiol (CBD) for people with Parkinson's who experience hallucinations or delusions

Research teams across the UK aim to investigate whether CBD is an effective treatment for hallucinations and delusions.

Who

120 people with Parkinson’s who:

• are over 40 years old

• have experienced any symptoms of psychosis for at least one month. This could include seeing, hearing, or feeling things that aren’t there and mistaking objects for other things (hallucinations). For example, a pile of clothes might look like a dog. Symptoms could also include unusual thoughts, beliefs, or worries that aren't based on reality (delusions)

• have been taking any Parkinson’s medications for at least one month

• are not taking clozapine

• and have someone who can attend study visits with them

What

If you are eligible to take part, you will either receive the study treatment (CBD) or a placebo treatment (such as a sugar pill) for 12 weeks.

You will be asked to attend up to 6 visits. Some of these can take place over the telephone or online, and others will need to take place at your local research centre or at your home. Each visit will last between 1 and 3 hours. During the visits, you may be asked to give blood samples, complete surveys, or physical examinations. 

You can also optionally take part in 2 MRI scans.

Find more information in the following participant information sheets:

Read the participant information sheet for people with Parkinson’s.

• Read the participant information sheet for accompanying loved ones or carers.

Interested in taking part?

Scroll down to find your nearest study site location, click on the arrow and contact the relevant research team. 

The deadline for taking part in this research is 1 March 2025.

If you have any questions, please contact the Research Team by email at [email protected].

More information

You can stay up to date with news from the study and meet the research team on Twitter @CANPDP_trial or Facebook at www.facebook.com/CAN.PDP

This is a phase 2 research study. Previous studies suggest that CBD may be useful in treating symptoms of psychosis, they also suggest that it is safe to use in older adults. Find out more about the different phases of medical research.

Deadline
Funded by

Parkinson's UK

Research
  • Treatments or therapies
Locations
Location

King's College Hospital, Denmark Hill
London
SE5 9RS
United Kingdom

Contact

Sara Pisani

Email: [email protected] 

Phone: 07936545178

 

Location

Institute of Psychiatry, Psychology and Neuroscience
16 De Crespigny Park
King's College London
London
SE5 8AF
United Kingdom

Contact

Sara Pisani

Email: [email protected]

Phone: 07936545178

Location

St George's University Hospitals NHS FT, Blackshaw Road,
London
SW17 0QT
United Kingdom

Contact

Joana Teixeira

Email: [email protected]

 

 

Location

Royal United Hospital, Combe Park
Bath, Avon
BA1 3NG
United Kingdom

Contact

Jessica Franks

Email: [email protected]

General email: [email protected]

Location

Royal Hallamshire Hospital, Broomhill, Glossop Rd
Sheffield
S10 2JF
United Kingdom

Contact

Anna Emery

Email: [email protected]

Katie Strobin 

Email: [email protected]

 

Location

St Peter's Hospital, Guildford St, Lyne,
Chertsey
KT16 0PZ
United Kingdom

Contact

Contact: Elizabeth Cruddas
 

Email: [email protected]

 

Location

Derbyshire Healthcare NHS Foundation Trust,
Centre for Research and Development, Kingsway Hospital, Kingsway
Derby
DE22 3LZ
United Kingdom

Contact

Caroline Cheetham

Email: [email protected]

 

Location

Royal Gwent Hospital, Cardiff Road,
Newport
NP20 2UB
United Kingdom

Contact

Clinical Trial Coordinator, Jemma Tuffney

Email: [email protected]

Location

Prince Phillip Hospital
Bryngwyn Mawr
Llanelli
SA14 8QF
United Kingdom

Contact

Linda O'Brien

Email: [email protected]

Daniel Sheehan

Email: [email protected]

Location

Wrexham Maelor Hospital, Croesnewydd Road,
Wrexham
LL13 7TD
United Kingdom

Contact

Clinical Research Specialist Officer, Claire Watkins

Email: [email protected]

Location

Cornwall Partnership NHS Foundation Trust, Carew House, Beacon Technology Park, Dunmere Rd,
Bodmin
PL31 2QN
United Kingdom

Contact

Research Office

Email: [email protected]

Phone: 01209 204020

Location

Withybush General Hospital
Fishguard Road
Haverfordwest
Pembrokeshire
SA61 2PZ
United Kingdom

Contact

Jan Phipps

Email: [email protected]

 

Location

Department of Research and Innovation (Sunderland Research Office) Education Centre
Sunderland Royal Hospital
Kayll Road, Sunderland
Tyne and Wear
SR4 7TP
United Kingdom

Contact

Susan Wilson 

Email: [email protected]

 

Location

NHS Lothian
Western General Hospital
Edinburgh
EH4 2XU
United Kingdom

Contact

Jessica Crossan
Email: [email protected]
Telephone: 01315 372 409
 

Location

NHS Tayside
Ninewells Hospital
Dundee
DD1 9SY
United Kingdom

Contact

Kate Ferguson
Email: [email protected]
Telephone: 01382 423 086

Location

NHS Grampian
Royal Cornhill Hospital
Cornhill Road
Aberdeen
AB25 2ZH
United Kingdom

Contact

Julie Scott
Email: [email protected]
Telephone: 01224 557 568