Sinemet supply issue update November 2018

Some Sinemet products continue to face intermittent shortages in the UK, according to manufacturer Merck Sharp & Dohme Limited (MSD).

In September we alerted health and social care professionals to supply issues with some Sinemet products in the UK and other countries due to manufacturing capacity constraints.

Parkinson's UK have remained in regular contact with the manufacturers of Sinemet, MSD, to understand the supply issues and what they're doing to ensure Sinemet is available for people with Parkinson's across the UK.

MSD have reported that they have been working hard to meet demand and keep their Sinemet products in stock. They have managed to do that for the majority of their products.

Sinemet 12.5/50mg 9x10 tablets, the most commonly used tablets, are in stock and there are no supply issues reported

For other Sinemet products:

  • Sinemet 10/100mg 10x10 tablets may be unavailable from now until mid-December when stock will be replenished.
  • Sinemet plus 25/100mg 10x10 tablets may be currently unavailable but stock will be replenished in early December.
  • Sinemet 25/250mg will not be in stock until the end of January 2019.

As the situation changes we will post further updates.

MSD has alerted the Department of Health, as well as pharmacy wholesalers, and is working to cascade this information through relevant channels.

How is this being communicated to people with Parkinson's?

An updated statement is available for people with Parkinson's, which has also been shared on social media. People with Parkinson's can contact the Parkinson's UK helpline to discuss concerns about supplies on 0808 800 0303.

I am a pharmacist – who can I contact about supply?

Pharmacists experiencing difficulties in getting hold of product from their wholesaler can contact MSD via details on their website.  

Parkinson's UK are monitoring Sinemet supply issues across the UK. If you are experiencing specific Sinemet supply issues please contact [email protected] with details of Sinemet products you are experiencing difficult with and the location of the relevant pharmacy.