Parkinson's medication: supply update

Getting your prescription

Pharmaceutical companies have shared they are facing supply problems with some medicines. Please check with your local pharmacy, as they may have your usual medicine in stock. 

However, if your area does have supply shortages you may not be able to get your usual prescription.

Alternatives may be suitable. Your doctor or pharmacist will discuss this with you.

Parkinson's drugs: current shortages 

Updated 29 April 2025.

Teva Pharmaceuticals

• Amantadine 50mg/5ml syrup is currently experiencing supply problems, which may last until the end of June 2025.
• Co-beneldopa 12.5mg/50mg capsules x 100 will experience supply problems until the end of May 2025.
• Pramipexole 0.26mg prolonged-release tablets x 30 are currently experiencing supply problems, which may last until the end of June 2025.
• Pramipexole 2.62mg prolonged-release tablets x 30 are currently experiencing supply problems, which may last until the end of September 2025.
• Pramipexole 3.15mg prolonged-release tablets x 30 are currently experiencing supply problems, which may last until the end of June 2025. 

Britannia

APO-go® (apomorphine hydrochloride) pre-filled syringes (PFS) are being discontinued and will no longer be available from April 2025. If you use an APO-go® PFS, your healthcare team should talk this through with you and you will decide together the best option for taking apomorphine.

APO-go® POD (apomorphine hydrochloride hemihydrate) 100mg/20ml solution for infusion cartridges remain available and can support increased demand.

Please see our apomorphine page for further information. If you have any concerns, please speak to your healthcare team or contact our helpline on 0808 800 0303.

Why the UK has medicine supply issues

The UK has some specific challenges, but the NHS is not alone in experiencing drug shortages. A recent European Association of Hospital Pharmacists survey reported that 95% of hospital pharmacists across Europe were experiencing shortages.

The British Medical Journal (BMJ) points to a combination of factors including:

• post pandemic factors
• global supply chain issues.

UK-specific challenges are reported to include:

• post-Brexit costs and paperwork
• a voluntary NHS annual spending cap on branded medicines.

For doctors and pharmacists

Please seek advice from your NHS pharmacy procurement specialist or the Specialist Pharmacy Service.

Staying up to date with supply issues

We'll post updates as pharmaceutical companies share them with us. They'll let us know what action they're taking to make sure medications are available for people with Parkinson's.