CHIEF-PD - Can rivastigmine, a Cholinesterase Inhibitor, help prevent falls in Parkinson's?

The aim of the research is to determine whether these drugs do help prevent falls. The research trial will be happening at 26 sites across the UK so do keep an eye out for new locations being added.

Who

600 people, over the age of 18, diagnosed with Parkinson's who have fallen in the past year.  You will need to be able to walk at least 10 meters without a walking aid or assistance and not be taking Cholinesterase Inhibitors (such as donepezil and rivastigmine).

What

You will be asked to attend 2 visits at the research site nearest you, one at the beginning of the research and one at the end (after 12 months). There is also the option to have these assessments done in your own home so you don't need to attend the local hospital. At the first visit you will be screened for eligibility and if found to be eligible you will be randomised to either receive the drug or a placebo and take part in a few assessments.

For full information about the research:

Please read the Participant Information Sheet and contact the site nearest you from the information below.

If there is not a site local to you and you would still like to take part please email [email protected] as new research centres are opening weekly.

Deadline
Funded by

NIHR Health and Technology Assessment.

Research
  • Care and services
  • I can do at home
  • Treatments or therapies
Locations
Location

Royal United Hospitals Bath NHS Foundation Trust
Combe Park
Bath
BA1 3NG
United Kingdom

Contact

Ruth Hamlin

[email protected]

01225 825797

Location

Fairfield General Hospital
Rochdale Old Road
Bury
BL9 7TD
United Kingdom

Contact

Linda Johnson, Sanniah Hussain, Rosane Joseph

[email protected]

0161 778 2634 or 0161 778 2559

Location

Barking, Havering and Redbridge University Hospitals NHS Trust
Queens Hosptial
Rom Valley Way
Romford
RM7 0AG
United Kingdom

Contact

Research team

Email: [email protected] 

Phone: 0117 428 3113

Location

Yeovil District Hospital NHS Foundation Trust
Higher Kingston
Yeovil
Somerset
BA21 4AT
United Kingdom

Contact

Alison Lewis

Email: [email protected]

Phone: 01935 384854

Location

University Hospitals Dorset
Christchurch Hospital
Fairmile Road
Christchurch
BH23 2JX
United Kingdom

Contact

Emma Gunter or Rochelle Hernandez

[email protected] or  [email protected]

0300 019 5284 or 0300 019 5136

Location

Charing Cross Hosptial
Fulham Palace Road
Imperial Memory Unit, 10 West
London
W6 8RF
United Kingdom

Contact

Raquel Lopes

Email: [email protected] 

Phone: 0203 3111 714 

Location

Salford Royal NHS Foundation Trust
Barnes Building
Stott Lane
Salford
M6 8HD
United Kingdom

Contact

Neurology Research Team 

Email: [email protected]

Phone: 0161 206 0534 

Location

Leeds General Infirmary
D Floor Martin Wing
Great George Street,
Leeds
LS1 3EX
United Kingdom

Contact

Prisca Mpofu 

Email: [email protected] 

Tel: 01133 925073

Location

Royal Derby Hosptial
Uttoexeter Road
Derby
DE22 3NE
United Kingdom

Contact

Melanie Hayman

Email: [email protected]

Phone: 01332 788912 or 07387 248757 

Location

Queen Elizabeth Hospital
Sheriff Hill
Gateshead
Tyne and Wear
NE9 6SX
United Kingdom

Contact

Research team

Email: [email protected]

Phone: 0191 4456317

Location

John Radcliffe Hospital
Headley Way
Headington
Oxford
OX3 9DU
United Kingdom

Contact

Lauren Whitestone

Email: [email protected]

Phone: 01865 234309

Location

The Walton Centre NHS Foundation Trust
Ground floor
Lower Lane
Liverpool
L9 7LJ
United Kingdom

Contact

Sarah Illingworth

Email: [email protected]

Phone: 0151 556 3963

Location

Prince of Wales Hospital
MPEC Block
Coity Rd
Bridfend
CF31 1RQ
United Kingdom

Contact

Research Team

Email: CwmTaf.R&[email protected]

Phone: 01656 752477

Location

University Hospital Plymouth NHS Trust
1 Roscoff Rise
Derriford
Plymouth
PL6 5FP
United Kingdom

Contact

Mariana Dobranszky-Oroian

Email: [email protected]

Phone: 01752 437485

Location

Musgrove Park Hospital
Old Building
Parkfield Drive
Taunton
TA1 5DA
United Kingdom

Contact

Alison Whitcher (Research Nurse)

E-mail: [email protected]

Phone: 01823 343635

Location

North Tyneside General Hospital
Rake Lane
North Shields
NE29 8NH
United Kingdom

Contact

R&D team

Email: [email protected]

Phone: 0191 2934087

Location

Norfolk and Norwich University Hosptial
Colney Lane
Norwich
NR4 7UY
United Kingdom

Contact

Dr Ruban Alagaratnam

Email: [email protected]

Phone: 01603 288177

Location

Barnsley Hospital
Gawber Rd
Barnsley
S75 2EP
United Kingdom

Contact

Research Team

Email: [email protected]

Phone: 01226 435084

Location

Southmead Hospital
Westbury on Trym
Bristol
BS10 5NB
United Kingdom

Contact

Catherine Watkins

Email: [email protected]

Phone: 0117 4148276

Location

Gloucestershire Royal Hospital
Great Western Road
Gloucester
GL1 3NN
United Kingdom

Contact

Susan Bullock

Email: [email protected]

Phone: 0300 4225478

Location

Homerton University Hospital
Homerton Row
London
E9 6SR
United Kingdom

Contact

Catherine Holbrook

Email: [email protected]

Phone: 0208 510 7412

Location

University Hospitals of Leicester NHS Foundation Trust
Leicester Royal Infirmary
Leicester
LE1 5WW
United Kingdom

Contact

Jessica Hailstone

Email: [email protected]

Phone: 0116 2586772

Location

Univeristy College Hosptial
UCL Queens Square Institute of Neurology
33 Queens Square
London
WC1N 3BG
United Kingdom

Contact

Angelina Manoharan

Email: [email protected]

Phone:  20 3448 8608