Has anyone experienced tingling hands and feet when taking mirapexin PR.

I do remember experiencing a kind of tingling of the toes at some stage, but I can't remember when.

What dosage are you on, Farhills, and did you transfer to the PR version fairly recently?

I am on 1.05 mg PR per day and suffer few (if any) side effects now, although it took at least 3 months for the PR version to settle down even though I had slid across from the same dosage of the non-PR version. I felt as if I had gone backwards for a time, the worst symptom being a strange kind of 'gloom' hovering over me.

Hi,
I get this too especially the awful white numb fingers and Im also on Mirapexin pr........but I have had this on and off for 15 years? Can even remember being tested for Raynauds and later just a few years ago seeing a vascular consultant for my purple hands and feet, he said I had poor circulation due to smoking (quit no improvement) but maybe it was PD?
I must admit that the white fingers are worse when driving and when cold.
jax

I'm on Mirapexin (4x0.26 tablets at night) and can't say I have noticed any negative side effects. I feel happy virtually all the time - Parkinson's must be good for me!

Does anyone know if it would make any diference if, instead of taking four 0.26 tablets before I go to bed, I took 2x0.52 or 1x1.05? My pharmacist has trouble getting the 0.26 ones, but I am not seeing the neurologist again until March, so can't get any official guidance. My GP seems to think it would be OK to take any of them providing they totalled up the same, but he is not an expert on Parkinson's.

Hi donna
i was on mirpexen for a while last year and the side effects was once i took the dosage i felt very strong and high for a few hours and when worn off i was looking for the next dose .that is how i felt on the mirapexin but everyone is different.

Hi Donna, I presume you are taking the prolonged release form of Mirapexin?
So you take the lot (4x0.26mg tablets)in one go. There is absolutely no reason why you cannot take the same amount in one/two or four tablet form. Why do you think this would make a difference? I would have thought you would prefer to take as few tablets as possible and therefore take the higher dose tablet.
It is normal to start very slowly on Mirapexin, to let your body get used to this drug, and increase the dose gradually. For this reason you start with the low dose (0.26) tablets, but once you reach your desired/maximum dose (which is the dose that gives you relief of your PD symptoms)most patients would take the required dose in as few tablets as possible.

Hi Donna, I'm on mirapexin, not the slow release version though, as Kate has said, the smaller tablets just allow you to alter the dose as you require (ie build up/reduce gradually), equating the dose with higher value tabs makes no difference. I take it three times per day and also take more in the first two doses than the night one, when I need it less. I'm on a total of 2.4mg per day and very fortunately, no side effects that I've noticed as yet. But you know to be wary of the side effects I'm sure.

I was taking 1.05 mg Mirapexin per day divided into four doses. Then I transferred to one 1.05 mg prolonged release tablet per day but it took me a while to get used to the difference.

However, it was worth persevering as any negative effects have now settled down and the convenience of taking only one tablet per day cannot be overestimated.

Hi Lily and all,
In response to the opening question regarding tingling.I have had no tingling sensations,in fact i have had no side effects whatsoever.When upping the dosage had a touch of feeling sickly but never felt the need for anti-sickness tabs.
My only concern is the variation and confusing way that everyones dosage is compiled.According to my leaflet,the following tabs are available.
0.088 mg
0.18 mg
0.35 mg
0.7 mg
1.1 mg
I was diagnosed in November 09,started Mirapexin May 10.Usual increased dosage until 2 x 0.18 mg tabs 3 times a day.In Nov 10 this was increased to 1 x 0.7 mg tab 3 times a day.This is what i take now.Working fine,no side effects,but doesent seem to correlate with others ive seen on here.
I'm on 3 x 0.7 a day which i assume is a total of 2.1 mg daily.Looking at the info sheet the maximum dose daily dose is 3.3 mg daily.Does this mean that i am 2/3 of the way towards the maximum dose in a short period of time,or have i got things wrong.
The meds work fine but i wish the dosage could be more straightforward.
All the best
Titan

Hi Titan

What was the reason for your dosage being almost doubled from the 'maintenance dose' (according to the leaflet) last November? Did you notice any difference when it was increased?