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BEST TIME TO TAKE MEDS

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hopefull

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37 posts

Posted - 26 May 2012 08:32

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Morning everybody


Can i have some feed back please from you all who take Requip XL .
Been on 8mg for some time don't sleep at all well approx 4hr per night,but feel very stiff and rigid tires on waking.
Wondered if i would be better taking Requip in the morning instead of evening.
Appreciate reply's ASAP

THANKS

turnip

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Posted - 26 May 2012 10:15

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Requip xl DOES NOT LAST 24 hrs. In the GSK tests peak dose was 6-10 hours. If you are a 6hr person, its elimination half-life is 6hr so 12 hrs after you have taken it you are well on the down slope (any chemists can feel free to correct this!).
My personal belief is that it is best taken in 3 roughly equally spaced out doses. Seemingly the AUC (area under the curve - time x availabilty) is considerably increased if taken with a fatty meal. Ropinerole and chips anyone?

Bethankit

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Posted - 26 May 2012 12:29

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I initially took my Requip XL at breakfast time, but was very sleepy in the afternoon and not sleeping well. I discussed this with my PD Nurse who advised me to gradually move the time, I have done this and now take my meds at 6pm now need to be in bed by 9pm and manage to sleep for 5 hours up to loo back to bed and then manage to sleep for another 3 - 4 hours. This has worked for me so maybe worth trying moving the time back until you find a time that suits you. Like turnip I don't think that requip xl lasts a full 24 hours.
Best wishes and let me know how you get on changing the time. smile

Mosie

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Posted - 26 May 2012 14:17

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I take 8mg at breakfast and have a lot of sleep problems. No medic has ever suggested taking it at a different time and I am given an 8mg pill, so no chance of spacing it myself. Sitting here a bit shell shocked.

elegant fowl

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Posted - 26 May 2012 15:42

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I use Requip XL. I take 8mg a day using a 4mg in the morning and another 4mg before bed.
I often get funny looks from doctors, researchers et al when I tell them that I'm not taking a single dose per day.
I dont think I have noticed a particular advantage to taking it at a particular time of day.
EF

mike 700

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Posted - 26 May 2012 16:22

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Hi Hopeful,

I take 14 mg of Requip XL anytime between 06.00 and 09.30 each day and it usually makes my head spin about 15-20 mins. Later, so I don't drive until this period is over.


I do sometimes feel sleepy after lunch, but so do Lions, and I'm putting this down to getting older, not turning into s big cat, but I sometimes get tired mid evening, but this could be boredom, so I try and keep my mind alert to get through it.

The Requip however does not last 24 hrs, and my walking and balance problems get worse in the evening.

Following my last visit to the PD nurse, I gradually moved my tablet taking towards the late evening, as I was also having sleep problems, but I soon moved it back to the morning, as it didn't help me sleep better, but what it did do was to make everything else worse.

Each to their own I guess, but it is worth talking to the pro's about it until they get thedose and timing right.

Good luck, know what your going thru.

Mike

turnip

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Posted - 26 May 2012 20:37

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Mosie
it varies a lot for different people - if its working for you statistics are irrelevant.

English Country Dancer

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Posted - 27 May 2012 00:35

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8 mg is not a high dose and you may need more to prevent stiffness if it is the only medication you take.John takes his 18mg Requip XL at 6pm because evenings are his busy time, but then he takes four doses of Sinemet throughout the day as well. This does not appear to have effected his sleep.

English Country Dancer

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Posted - 27 May 2012 00:41

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PS.If anything his sleep improved when he went onto the XL version of Requip and we put that down to being medicated throughout the night.He no longer needs siestas. Just goes to show everybody is different

Big C

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Posted - 28 May 2012 22:48

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I am on requip xl 4mg per day, i used to take it at breakfast but found by mid afternoon i was falling asleep. My consultant recomended taking it at bed time and i feel much more alert in the day, i just have a problem waking up! I supose i should count myself lucky im on such a low dose!

Big c