I was dx some 18 months ago. 8 months ago, my nutricionist (which is also a GP) suggested I take L-Tyrosine supplements (1,000 mg/day every morning, with a glass of water 20 mins before eating/drinking any foods/juices, to ensure it's properly absorbed). His logic was that Tyrosine is supposed to boost mental alertness and energy (I complained of persistent tiredness) and that my tests showed I had low levels of Homovanillic acid (which suggests low levels of dopamine - unsurprising given PD). I've been taking these supplements and feel it does help with the alertness and energy and so far I feel no negative side effects at all. My only concern is that tyrosine is the main precursor to l-dopa (i.e., the main ingredient our brains use to create l-dopa), so I wonder if taking these supplements is a disguised way to take l-dopa (which I'm not taking yet). In addition to these Tyrosine supplements, I'm currently taking Azilect, CoQ10, vit C, Vit E, plus other stuff my tests showed I was low on (vit D, iodine, magnesium). I'm also taking some stuff which is supposed to help with inflammation (there are some hypothesis of inflammation being linked to PD and my tests show a few signs of inflammation). I've also adapted my diet and am doing some regular sports. So far, my PD symptoms remain very light and don't seem to be progressing much (or even at all), though I have no idea if any of this stuff I'm doing is having any impact or if it's just the way it goes anyway.
I've discussed the Tyrosine supplements with the 2 neurologists that I see. None had any clear view on any possible impact of taking Tyrosine supplements for PD. The one that seemed most informed about it said she knew of no studies showing that Tyrosine supplements could impact PD in any clear way, and clearly of no long-term studies. She was even unsure if Tyrosine, taken in supplements, would even make it to one's brain. She didn't know either of anything that could count as a serious drawbacks of taking them. Her only words of caution were: (a) over-the-counter supplements (like Tyrosine's) are somewhat riskier because they are subject to less stringent quality controls than prescription stuff, and (b) taking stuff that hasn't been tried and tested for PD may always turn out to have negative consequences. The other neurologist was even less helpful.
I personally have no idea if my Tyrosine supplements really have any impact on my PD. I can't really feel any difference in my PD symptoms after taking it. They don't get noticeably better after I take it, nor worsen when I don't take them (and sometimes I don't take them for a few days)... but my PD symptoms are very light and somewhat intermittent, so it's difficult for me to really tell.
So, I was wondering if anyone knows anything more about Tyrosine supplements or has had any experience with it.
Thanks in advance,