Researchers study the 'brain on a microchip'

13 August 2010

A new way of studying nerve cells has been developed by Canadian researchers and is highlighted in the journal Biomedical Microdevices this month.

The research team are using networks of nerve cells mounted on silicon chips to provide a unique window into the brain. Dubbed the 'brain on a microchip' this technique allows scientists to watch nerve cells in action.

Watching nerve cells in action

Previously it took scientists years of training to learn how to record nerve cell activity, and it was only possible to monitor one or two cells at a time.

The research team have now developed a 'neurochip' that means complex networks of cells can be placed on a chip and observed in minute detail.

Analysing groups of brain cells simultaneously as they work together will help track the subtlest changes in brain activity involved in conditions like Parkinson's.

Potential for Parkinson's research

People with Parkinson's don't have enough of a chemical called dopamine because some nerve cells in their brains have died. But how and why these nerve cells die is still unknown.

Dr Kieran Breen, Director of Research and Development comments:

"Studying the 'brain on a microchip' could help us understand what goes wrong in the nerve cells affected in Parkinson's.

"There are also exciting possibilities for using these ‘neurochips’ as a tool for rapid screening of potential new drugs."

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