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Lesioning techniques

Lesioning is a form of surgery used to treat some of the symptoms of Parkinson's

SurgeryLesioning techniques involve making selective damage (a lesion) to certain cells within specific areas of the brain.

The target site is located with the aid of computer technology. An electrode is then inserted with its tip at the optimum point.

A small destructive lesion is made by passing an electric current through the tip.

These lesions are known to have a beneficial effect on some Parkinson's symptoms.

Pallidotomy

Pallidotomy is the most common form of lesioning technique used.

The target site is located in the part of the brain known as the globus pallidus.

Pallidotomy is most important for its effect on rigidity and akinesia (slowness of movement), and reductions in the sudden, involuntary movements (dyskinesia) that can result from drug therapy.

Stereotactic thalamotomy

Stereotactic thalamotomy is recommended mainly for patients with a severe or drug resistant tremor, especially when one side of the body is afflicted more than the other.

Thalamotomy is used mainly to treat tremor.

Patient C's experience of stereotactic thalamotomy is based on a true story. The name has been witheld to protect confidentiality.

Subthalamotomy

Subthalamotomy has been performed by neurosurgeons at a few hospitals.

This procedure involves making a destructive lesion in the subthalamic nucleus rather than implanting an electrode as is the case with subthalamic stimulation.

Subthalamotomy is still experimental. It has not gained popularity because of the perceived high risk and the uncertainty about its long term effects in a progressive condition.

You can read more on lesioning and other forms of surgery for Parkinson's in our Surgery and Parkinson's booklet

More forms of surgery for Parkinson's

Return to the surgical treatments of Parkinson's main page

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