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Lesioning surgery for Parkinson's

Although the main treatment for Parkinson's is medication, lesioning is one of the types of surgery available to treat the symptoms of the condition.

SurgeryLesioning involves making selective damage (a lesion) to some of the cells in a target area of the brain.

The target site is found using a brain scan. An electrode is then inserted into the site and an electric current is passed through the tip. This causes damage to some of the cells that control movement.

This may reduce movement symptoms, such as tremor or involuntary movements (dyskinesia).

Lesioning surgery can be an effective treatment for Parkinson's, but it isn't a recommended choice for most people, because lesioning may cause irreversible side effects.

Pallidotomy

Pallidotomy involves making a destructive lesion in part of the brain called the globus pallidus.

The main benefit of this type of surgery is that it may reduce involuntary movements (dyskinesia), which can be one of the side effects of Parkinson's medication. But it can also help with rigidity and slowness of movement.

Thalamotomy

Thalamotomy involves making a destructive lesion in part of the brain called the thalamus. The technique is now only used in rare cases, mainly to treat tremor.

The procedure is usually done on one side only, because bilateral (both sides) thalamotomy is thought to be much more risky.

Read about a person's experience of thalamotomy

Subthalamotomy

This involves making a destructive lesion in part of the brain called the subthalamic nucleus. This technique has been performed by some neurosurgeons, mostly in countries where deep brain stimulation surgery is not available.

It is not certain what the long-term effects of subthalamotomy are.

More forms of surgery for Parkinson's

You can read more on lesioning techniques and other forms of surgery for Parkinson's in our Surgery for Parkinson's booklet.

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